Massive Cerebral Venous Sinus Thrombosis as an Unexpected Complication of Severe Hyperthyroidism

Abstract

Cerebral venous sinus thrombosis (CVST) is a rare but potentially fatal neurological condition frequently associated with prothrombotic states. Identifying the underlying cause of CVST is crucial but can be challenging, especially when it is reported as uncommon. Here, we present a case of a previously healthy 31-year-old Malay man who presented with massive CVST complicated with status epilepticus and arrhythmia in the setting of undiagnosed severe hyperthyroidism. The patient subsequently improved with intensive care therapy, thyroid storm protocol treatment, and antiplatelet medications. This case highlights the need to rule in hyperthyroidism in patients with atypical neurological symptoms, particularly CVST, even in the absence of associated risk factors.