Comparison of antimicrobial activity of crude extracts of Piper betle, Aloe vera, solanum lycopersicum, cinnamomum zeylanicum and cucumis sativus against acne inducing bacteria

Abstract

Acne vulgaris is a typical skin disorder among adolescence, causing inflammation of pilosebaceous follicle which characterized by comedones, papules, pustules, cysts, nodules and often scars in face, neck, upper trunk and arms. Propionibacterium acnes and Staphylococcus epidermidis have been recognized that play as a major role in acne formation. This study was conducted to compare the antimicrobial activity of five plant extracts namely Piper betle, Aloe vera, Solanum lycopersicum, Cinnamomum zeylanicum and Cucumis sativus against P. acnes and S. epidermidis. The well diffusion assay was used to determine the sensitivity of the samples, while the liquid dilution method was used for the determination of the minimal inhibition concentration (MIC). The result showed a remarkable antibacterial activity of Piper betle extract compared to other plant extracts and Doxycycline (positive control) against both of acne-inducing bacteria, P. acnes and S. epidermidis. 

    

 Keywords: : Acne-inducing bacteria; antimicrobial activity; sensitivity